Peptide vs small molecule — the practical consequences
Ipamorelin is a peptide, so it ships lyophilised and cold-chain packed, needs bacteriostatic water to reconstitute, and is stored at 2-8°C once mixed. It has a short reported duration in published work.
MK-677 is not a peptide at all. It is a small molecule that is orally active and stable at room temperature, which makes storage and handling far simpler for a lab with limited cold storage.
Selectivity is the other axis: ipamorelin is described in the literature as a comparatively selective secretagogue, which is why it appears in studies isolating a single pathway.
What ships with each order
Ipamorelin orders are usually placed alongside bacteriostatic water and syringes — we stock both, and they travel in the same cold-chain parcel at no extra shipping cost.
MK-677 needs no reconstitution supplies. Both carry a lot number matched to a Certificate of Analysis.
Questions people ask
- Is MK-677 a peptide?
- No. MK-677 (ibutamoren) is a non-peptide small molecule that acts on the ghrelin receptor. Ipamorelin is a genuine pentapeptide.
- Does ipamorelin need refrigeration?
- Yes. It ships lyophilised and cold-chain packed, stored at -20°C long-term or 2-8°C short-term, and refrigerated at 2-8°C after reconstitution.
- Which is easier to store?
- MK-677, since it is room-temperature stable and needs no reconstitution. Ipamorelin requires cold storage and bacteriostatic water.
- Do I need syringes and bacteriostatic water for either?
- For ipamorelin, yes — we stock bacteriostatic water, insulin syringes and alcohol prep swabs. MK-677 requires none of them.